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Happy Hormones Ingredients: Research Papers

Happy Hormones Ingredients: Research Papers

A common misconception is that natural medicines are not scientifically proven. In fact, there is a huge bank of research and clinical trials validating natural medicines. Another misconception is that natural medicines are not regulated and make false claims.

In Australia via the TGA and in the USA via the FDA, all health claims need to be substantiated. There are quite strict guidelines and any claims made without scientific validation come with heavy fines and product delisting. Below are some of the scientific studies used in the formulation of Happy Hormones and the claims validation process. 

Sage (Salvia officinalis)

1.
An extract of Salvia (sage) with anticholinesterase properties improves memory and attention in healthy older volunteers.

Authors: Andrew B. Scholey, Nicola T. J. Tildesley, Clive G. Ballard, Keith A. Wesnes Andrea Tasker, Elaine K. Perry, David O. Kennedy
Publication: Psychopharmacology (Berl). 2008 May;198(1):127-39.
Pubmed Data: DOI 10.1007/s00213-008-1101-3. Epub 2008 Mar 19.

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2.
First time proof of sage's tolerability and efficacy in menopausal women with hot flushes.

Authors: S. Bommer, P. Klein, A. Suter
Publication: Adv Ther. 2011 Jun;28(6):490-500.
Pubmed Data: DOI 10.1007/s12325-011-0027-z. Epub 2011 May 16.

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Black Cohosh

3.
Black cohosh with or without St. John's wort for symptom-specific climacteric treatment--results of a large-scale, controlled, observational study.

Authors: Briese V(1), Stammwitz U, Friede M, Henneicke-von Zepelin HH.
Publication: Maturitas. 2007 Aug 20;57(4):405-14.
Pubmed Data: Epub 2007 Jun 21.

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4.
Black cohosh improves objective sleep in postmenopausal women with sleep disturbance.

Authors: Jiang K(1), Jin Y, Huang L, Feng S, Hou X, Du B, Zheng J, Li L.
Publication: Climacteric. 2015;18(4):559-67.
Pubmed Data: DOI 10.3109/13697137.2015.1042450. Epub 2015 May 22.

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5.
Phyto-Female Complex for the relief of hot flushes, night sweats and quality of sleep: randomized, controlled, double-blind pilot study.

Authors: Rotem C(1), Kaplan B.
Publication: Gynecol Endocrinol. 2007 Feb;23(2):117-22.
Pubmed Data: DOI: 10.1080/09513590701200900

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6.
Menopause: a standardized isopropanolic black cohosh extract (remifemin) is found to be safe and effective for menopausal symptoms.

Authors: Ross SM(1).
Publication: Holist Nurs Pract. 2012 Jan-Feb;26(1):58-61.
Pubmed Data: DOI 10.1097/HNP.0b013e31823d1f67.

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7.
Efficacy and tolerability of a medicinal product containing an isopropanolic black cohosh extract in Chinese women with menopausal symptoms: a randomized, double blind, parallel-controlled study versus tibolone.

Authors: Bai W(1), Henneicke-von Zepelin HH, Wang S, Zheng S, Liu J, Zhang Z, Geng L, Hu L, Jiao C, Liske E.
Publication: Maturitas. 2007 Sep 20;58(1):31-41.
Pubmed Data: DOI 10.1016/j.maturitas.2007.04.009. Epub 2007 Jun 22.

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8.
Black cohosh and fluoxetine in the treatment of postmenopausal symptoms: a prospective, randomized trial.

Authors: Oktem M(1), Eroglu D, Karahan HB, Taskintuna N, Kuscu E, Zeyneloglu HB.
Publication: Advances in Therapy 2007 Mar-Apr;24(2):448-61. 

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Maca

9.
Maca reduces blood pressure and depression, in a pilot study in postmenopausal women.

Authors: Stojanovska L(1), Law C, Lai B, Chung T, Nelson K, Day S, Apostolopoulos V, Haines C.
Publication: Climacteric. 2015 Feb;18(1):69-78.
Pubmed Data: DOI 10.3109/13697137.2014.929649. Epub 2014 Aug 7.

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10.
Beneficial effects of Lepidium meyenii (Maca) on psychological symptoms and measures of sexual dysfunction in postmenopausal women are not related to estrogen or androgen content.

Authors: Brooks NA(1), Wilcox G, Walker KZ, Ashton JF, Cox MB, Stojanovska L.
Publication: Menopause. 2008 Nov-Dec;15(6):1157-62.
Pubmed Data: DOI 10.1097/gme.0b013e3181732953. 

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11.
Therapeutic Effects of Pre-Gelatinized Maca (Lepidium Peruvianum Chacon) used as a Non-Hormonal Alternative to HRT in Perimenopausal Women - Clinical Pilot Study.

Authors: Meissner HO(1), Reich-Bilinska H, Mscisz A, Kedzia B.
Publication: Int J Biomed Sci. 2006 Jun;2(2):143-59.

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Gymnema Sylvestre

12.
An open label study on the supplementation of Gymnema sylvestre in type 2 diabetics.

Authors: Kumar SN(1), Mani UV, Mani I.
Publication: J Diet Suppl. 2010 Sep;7(3):273-82.
Pubmed Data: DOI 10.3109/19390211.2010.505901.

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Chaste Berry

13.
Effects of a combination of Hypericum perforatum and Vitex agnus-castus on PMS-like symptoms in late-perimenopausal women: findings from a subpopulation analysis.

Authors: van Die MD(1), Bone KM, Burger HG, Reece JE, Teede HJ.
Publication: J Altern Complement Med. 2009 Sep;15(9):1045-8.
Pubmed Data: DOI 10.1089/acm.2008.0539.

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14.
Treatment of premenstrual syndrome with a phytopharmaceutical formulation containing Vitex agnus castus.

Authors: Loch EG(1), Selle H, Boblitz N.
Publication: J Womens Health Gend Based Med. 2000 Apr;9(3):315-20.

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15.
Phyto-Female Complex for the relief of hot flushes, night sweats and quality of sleep: randomized, controlled, double-blind pilot study.

Authors: Rotem C(1), Kaplan B.
Publication: Gynecol Endocrinol. 2007 Feb;23(2):117-22.
Pubmed Data: DOI: 10.1080/09513590701200900

Download the PDF


Red Clover

16.
Improvement of postmenopausal depressive and anxiety symptoms after treatment with isoflavones derived from red clover extracts.

Authors: Lipovac M(1), Chedraui P, Gruenhut C, Gocan A, Stammler M, Imhof M.
Publication: Maturitas. 2010 Mar;65(3):258-61.
Pubmed Data: DOI 10.1016/j.maturitas.2009.10.014. Epub 2009 Nov 30.

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17.
Effectiveness of Red Clover in alleviating menopausal symptoms: a 12-week randomized, controlled trial.

Authors: Shakeri F(1), Taavoni S, Goushegir A, Haghani H.
Publication: Climacteric. 2015;18(4):568-73.
Pubmed Data: DOI 10.3109/13697137.2014.999660. Epub 2015 Feb 24.

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18.
The effect of red clover isoflavone supplementation over vasomotor and menopausal symptoms in postmenopausal women.

Authors: Lipovac M(1), Chedraui P, Gruenhut C, Gocan A, Kurz C, Neuber B, Imhof M.
Publication: Gynecol Endocrinol. 2012 Mar;28(3):203-7.
Pubmed Data: DOI 10.3109/09513590.2011.593671. Epub 2011 Aug 26.

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19.
Influence of red clover-derived isoflavones on serum lipid profile in postmenopausal women.

Authors: Terzic MM(1), Dotlic J, Maricic S, Mihailovic T, Tosic-Race B.
Publication: J Obstet Gynaecol Res. 2009 Dec;35(6):1091-5.
Pubmed Data: DOI 10.1111/j.1447-0756.2009.001059.x.

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20.
Effect of Trifolium pratense-derived isoflavones on the lipid profile of postmenopausal women with increased body mass index.

Authors: Chedraui P(1), San Miguel G, Hidalgo L, Morocho N, Ross S.
Publication: Gynecol Endocrinol. 2008 Nov;24(11):620-4.
Pubmed Data: DOI 10.1080/09513590802288283.

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Dandelion Root

21.
The diuretic effect in human subjects of an extract of Taraxacum officinale folium over a single day.

Authors: Clare BA(1), Conroy RS, Spelman K.
Publication: J Altern Complement Med. 2009 Aug;15(8):929-34.
Pubmed Data: DOI 10.1089/acm.2008.0152.

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Passiflora

22.
Passiflora incarnata Linneaus as an anxiolytic before spinal anesthesia.

Authors: Aslanargun P(1), Cuvas O, Dikmen B, Aslan E, Yuksel MU.
Publication: J Anesth. 2012 Feb;26(1):39-44.
Pubmed Data: DOI 10.1007/s00540-011-1265-6. Epub 2011 Nov 3.

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23.
A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality.

Authors: Ngan A(1), Conduit R.
Publication: Phytother Res. 2011 Aug;25(8):1153-9.
Pubmed Data: DOI 10.1002/ptr.3400. Epub 2011 Feb 3.

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24.
Preoperative oral Passiflora incarnata reduces anxiety in ambulatory surgery patients: a double-blind, placebo-controlled study.

Authors: Movafegh A(1), Alizadeh R, Hajimohamadi F, Esfehani F, Nejatfar M.
Publication: Anesth Analg. 2008 Jun;106(6):1728-32.
Pubmed Data: DOI 10.1213/ane.0b013e318172c3f9.

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 Jeff Butterworth

 

Jeff Butterworth

Jeff Butterworth B.App. Sc, N.D is a Naturopath with over 25 years experience, specialising in women's health. Jeff developed the Happy Healthy YOU program after discovering women needed simple and effective natural solutions to their hormonal concerns.

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Jodie L. (Brisbane, AU)
Amazing

I have been taking HH for over a year and each time i think I can go without them I notice such a decrease in energy and mood. They have made a significant difference to my life and mood. I am a shift worker and I highly recommend for any women peri menopausal and low energy levels.

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Sheena H.H. (Sydney, AU)
I wish I'd tried HH sooner.

100 Happy Hormone tablets later and WHAT a difference. I cant imagine not taking this little supplement of sanity every day. If you are tossing up needs v's wants .... HH are a need, do this for yourself. I wish I had've ordered sooner.

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Suzanne F.F. (Millendon, AU)
Happy Hormones is my life saver

I started going through peri menopause and am having a period every 3-5 months. My biggest symptom beside insomnia is hot flushes. I was having one every 10 minutes and I became a very horrible person as I just couldn't stand them. Enter Happy Hormones, I was having 2 morning and night and it wasn't doing anything and then someone on the FB page suggested 3 morning and night and for that I am forever grateful as now I am not grumpy all the time and the hot flushes are like maybe 5 a day now. I am sure my husband and kids thanks you more :)

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Angela B. (Perth, AU)
Mother's Little Helper

My great friend Lori Woodhouse recommended I take Happy Hormones almost four years ago. It is the only supplement I have really noticed a significant improvement in my well being. I haven't gone without it since! I went from struggling to cope with being a working mum to enjoying parenting, and being able to balance life. I returned to uni whilst still working, finished my degree, and accepted a new job which is interesting, family friendly and challenging. I don't believe I could have managed all that in the past 4 years without my daily dose of Happy Hormones, and of course the support of my wonderful friend Lori Woodhouse. Lori also landed her dream job in that time, which combines her skills as a Registered Nurse with a passion for health at Happy Healthy You! This is us at my 50th Birthday Lunch just four weeks ago!

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Denise B. (Melbourne, AU)
Thank goodness for your products

I use both Happy hormones and happy liver, although I am 68 I still get hot flushes, my recent blood test my liver is great
And I am very happy to say my hot flushes are gone Tks to your wonderful products, they travel all over Australia with me and I have spread the word about them. Tks sooooo much

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